Table 1. Numbers of significant genes identified by analyzing the SCZ1 data.
Enhancer | Enhancer + gene body | Gene body (STD) | TWAS | ||||||
---|---|---|---|---|---|---|---|---|---|
MCF7 | Hippo | MCF7 | Hippo | YFS | NTR | METSIM | CMC | ||
# genes | 8589 | 3363 | 9127 | 4600 | 22842 | 4697 | 2452 | 4665 | 5412 |
SPU(1) | 14/12/11a | 8/6/6 | 20/19/18 | 15/13/14 | 36/32/34 | 14/11/14 | 10/6/10 | 8/5/7 | 16/10/13 |
SPU(2) | 35/25/29 | 9/9/9 | 39/29/33 | 46/34/40 | 89/77/84 | 31/25/26 | 27/19/26 | 23/14/23 | 39/25/34 |
The numbers a/b/c in each cell indicate the numbers of (a) significant genes; (b) significant genes that covered one or more genome-wide significant SNPs within an extended gene region kb in the SCZ1 data; (c) significant genes that covered one or more genome-wide significant SNPs within an extended gene region kb in the SCZ2 data.
Some genome-wide significant loci in the SCZ1 data were no longer significant in the SCZ2 data. For example, gene CUL9 contained some significant SNPs in the SCZ1 data (with the most significant SNP ) but did not contain any significant SNPs in the SCZ2 data (with the smallest ).