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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Alcohol Clin Exp Res. 2018 May 21;42(7):1281–1290. doi: 10.1111/acer.13760

Figure 4. Withdrawal from CIE increases irritability-like behavior in both C57 and DBA mice.

Figure 4

C57 (A-B; Air, n=16; CIE, n=12) and DBA (C-D; Air, n=5; CIE, n=5) mice were tested in the bottle brush test 3-7 days into withdrawal from 6 weeks of chronic intermittent ethanol (CIE) inhalation. A, C: Number of aggressive responses. B, F: Number of defensive responses. *, effect of treatment. #, effect of time. One symbol, p<0.05; two symbols, p<0.01; three symbols, p<0.001.