Table 1.
Cardiovascular Risk Factors and Biomarkers in the Cohort Random Sample and Cardiovascular Diseases Cases
| CRS* N = 1,104 |
Incident Stroke N = 646 |
Pstroke vs CRS | Incident CHD N = 654 |
PCHD vs. CRS | |
|---|---|---|---|---|---|
| Age (mean, SD) | 65 (7) | 70 (9) | <0.001 | 69 (9) | <0.001 |
| Male (N, %) | 530 (45%) | 308 (51%) | 0.008 | 387 (62%) | <0.001 |
| Black (N, %) | 541 (42%) | 261 (44%) | 0.36 | 281 (45%) | 0.43 |
| Region (N, %) | - | - | - | - | - |
| Belt | 369 (35%) | 210 (35%) | - | 250 (40%) | - |
| Buckle | 189 (18%) | 119 (20%) | 0.72 | 102 (16%) | 0.14 |
| Nonbelt | 510 (47%) | 270 (45%) | - | 271 (44%) | - |
| Current Smoking (N, %) | 155 (14%) | 108 (18%) | 0.03 | 131 (21%) | <0.001 |
| Diabetes (N, %) | 226 (22%) | 163 (28%) | 0.007 | 192 (32%) | <0.001 |
| Baseline Cardiovascular Disease (N, %) | 201 (17%) | 167 (28%) | <0.001 | 28 (4%) | <0.001 |
| Baseline CHD (N, %) | 188 (16%) | 162 (27%) | <0.001 | - | - |
| Baseline Stroke (N, %) | 82 (7%) | - | - | 66 (11%) | <0.001 |
| Atrial Fibrillation (N, %) | 68 (8%) | 60 (15%) | 0.06 | 63 (10%) | 0.008 |
| Left Ventricular Hypertrophy (N, %) | 105 (9%) | 88 (15%) | <0.001 | 72 (12%) | 0.02 |
| Body Mass Index kg/m2 (Mean, SD) | 29 (6) | 29 (6) | 0.02 | 29 (6) | 0.36 |
| Systolic Blood Pressure mmHG (Mean, SD) | 127 (15) | 134 (18) | <0.001 | 135 (20) | <0.001 |
| Blood Pressure Medications (N, %) | 551 (52%) | 286 (66%) | <0.001 | 360 (60%) | <0.001 |
| Total Cholesterol mg/dL (Mean, SD) | 190 (37) | 191 (43) | 0.79 | 192 (42) | 0.73 |
| HDL Cholesterol mg/dL (mean, SD) | 52 (16) | 50 (17) | 0.005 | 47 (14) | <0.001 |
| Taking cholesterol medications (n, %) | 339 (35%) | 203 (34%) | 0.90 | 168 (27%) | 0.41 |
| Factor VIII % (mean, SD) | 121 (44) | 132 (49) | <0.001 | 136 (57) | <0.001 |
| Protein C % (mean, SD) | 122 (22) | 120 (23) | 0.05 | 120 (28) | 0.054 |
*
Weighted percent