Table 1.

Transcriptome-based molecular subtypes of human pancreatic cancer and stroma and their effects on survival

Classification	Molecular subtype	Effect on survival
Collisson et al. [3]	Quasimesenchymal	↓1
	Exocrine-like
	Classical
Bailey et al. [4▪▪]	Squamous	↓1
	ADEX2
	Pancreatic progenitor	↓3
	Immunogenic	↓4
Moffitt et al. [5]	Basal-like5	↓1
	Classical6
	‘Normal’ stroma
	‘Activated’ stroma	↓7

¹This group has the worst survival in the respective classification.

²Aberrantly differentiated endocrine and exocrine.

³Within the progenitor group, patients with a higher expression of genes in this gene program have a worse prognosis.

⁴Within the immunogenic group, high macrophage and T-cell coinhibition signatures are associated with a worse prognosis.

⁵The basal group only partially overlaps with the quasimesenchymal group.

⁶The classical group only partially overlaps with the Collisson classical group.

⁷‘Activated’ stroma was associated with a worse prognosis when compared with ‘normal’ stroma. Stromal types are not tumor subtype specific.

The different classification schemes by the authors are shown. The matching colors correspond to overlapping groups under the different classification schemes. The Moffitt tumor subtypes only have partial overlap with the other corresponding groups.