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Schizophrenia risk gene networks untargeted by current antipsychotics. Highlighted schizophrenia risk genes with >2 steps/edges to an antipsychotic drug target genes, with their first interactome neighbors. a) The nicotinic acetylcholine receptor (nAChRs) genes CHRNA3, CHRNA5 and CHRNB4, b) Protocadherin alpha cluster genes, PCDHA1 - PCDHA10, and c) HCN1. We show three examples here, see Supplementary Figure 1 for the full network.
