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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Curr Protoc Mol Biol. 2018 Jun 19;123(1):e64. doi: 10.1002/cpmb.64

Figure 1. In Situ Capture of Locus-Specific Chromatin Interactions by Biotinylated dCas9.

Figure 1

Schematic of dCas9-mediated CAPTURE of cis-element-associated chromatin interactions. The three components of the CAPTURE system: a FLAG-biotin acceptor (FB)-tagged dCas9, a biotin ligase BirA, and a target-specific sgRNA. This figure was reproduced from (Liu et al., 2017) with permission from Elsevier.