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Z-average diameters measured by DLS for lyophilized and reconstituted samples from DoE1 (A), DoE2 (B), and DoE3 (C). Particle size measured after lyophilization and reconstitution. Trends between disaccharide type for DoE1 and glycine concentration for DoE2 are apparent. See Tables S2–S4 for sample compositions.
Abbreviations: DLS, dynamic light scattering; DoE, design of experiments.
