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. 2018 Jul 2;8:9939. doi: 10.1038/s41598-018-26812-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Chart comparing the percentage of models in each step of the refinement pipeline that improved the GDT_HA of the original model provided by CASP organizers. The steps are identified as follows: (1) models generated by Foldit players (Foldit-All), (2) clusters (Foldit Clusters), (3) clusters refined by KoBaMIN (Foldit Koba), (4) selection by McGuffin (K-McG), (5) selection by Wallner/ProQ2 (BW-Kb-BW), (6) selection by SVLab of KoBaMIN-refined clusters (SVLab-Koba), and (7) selection by SVLab based on unrefined clusters (SVLab-Clusters).