Table 3.

Diagnosis established by the CDEPA instrument and scores of the study assessments

	Diagnosis with the CDEPA questionnaire
	Advanced mean ± SD (95% CI)	Non-advanced mean ± SD (95% CI)	P value
Hoehn and Yahr stage	3.3 ± 0.9 (3.1–3.5)	2.0 ± 0.7 (1.8–2.2)	0.001
SCOPA motor scale
Examination (motor evaluation)	16.1 ± 6.4 (14.8–17.3)	6.6 ± 4.1 (5.6–7.7)	0.001
Activities of daily living	10.3 ± 4.5 (9.4–11.2)	2.9 ± 2.6 (2.2–3.5)	0.001
Dyskinesias	2.2 ± 1.9 (1.8–2.6)	0.5 ± 1.2 (0.1–0.8)	0.001
Motor fluctuations	2.7 ± 1.6 (2.4–3.0)	0.6 ± 1.1 (0.4–0.9)	0.001
Total scores	30.8 ± 11.72 (28.6–33.0)	10.6 ± 7.1 (8.8–12.35)	0.001
Non-motor symptoms scale
Cardiovascular	1.2 ± 2.2 (0.8–1.7)	0.5 ± 1.3 (0.2–0.9)	0.003
Sleep/fatigue	11.4 ± 8.7 (9.8–13.1)	5.3 ± 5.7 (3.9–6.7)	0.001
Mood/cognition	12.4 ± 15.3 (9.5–15.3)	4.8 ± 11.2 (2.0–7.6)	0.001
Perceptual problems/hallucinations	1.9 ± 4.3 (1.1–2.7)	0.4 ± 1.8 (−0.1−0.8)	0.001
Attention/memory	5.9 ± 8.0 (4.4–7.4)	2.6 ± 5.1 (1.3–3.9)	0.001
Gastrointestinal tract	5.8 ± 6.3 (4.6–7.0)	2.3 ± 3.3 (1.5–3.1)	0.001
Urinary function	9.8 ± 8.7 (8.1–11.4)	4.8 ± 6.6 (3.2–6.4)	0.001
Sexual function	4.4 ± 6.1 (3.2–5.5)	3.2 ± 5.8 (1.8–4.7)	0.457
Miscellaneous	8.2 ± 7.5 (6.8–9.6)	4.8 ± 4.9 (3.6–6.0)	0.005
Total score	60.9 ± 41.0 (53.1–68.7)	29.0 ± 29.6 (21.4–36.2)	0.001
Clinical Impression of severity index for PD	13.0 ± 4.0 (12.2–13.8)	5.1 ± 3.2 (4.3–6.0)	0.001