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. 2018 Jul 2;150(7):949–968. doi: 10.1085/jgp.201711868

Figure 11.

Figure 11.

MD simulations show the paracellular claudin-15 channels are cation and size selective. (A–E) I-V curves were calculated for systems containing 110 mM solutions of NaCl (A), methylammonium chloride (MACl; B), ethylammonium chloride (EACl; C), tetramethylammonium chloride (TMACl; D), and tetraethylammonium chloride (TEACl; E). Cationic and anionic currents are shown in blue and orange, respectively. (F) Conductance of the ions (Na+, MA+, TMA+, TEA+, and Cl) for the WT channel. Error bars represent SEM.