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. 2018 Jul 2;150(7):949–968. doi: 10.1085/jgp.201711868

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© 2018 Khalili-Araghi et al.

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Figure 2. — Claudin-15 channel conductance is saturated within the physiological range of Na⁺ and Cl⁻. (A–D) I-V plots are calculated with 50 mM of Na⁺ and no Cl⁻ (A), neutralized with 24 TEA⁺ and 60 mM NaCl (B), 110 mM NaCl (C), or 170 mM NaCl (D). (E) Conductance of the Na⁺ ions for the WT channel for the four systems above.