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. 2018 Jul 2;215(7):1929–1945. doi: 10.1084/jem.20170484

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© 2018 Mansour et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure 7. — Thymuses of Tg(rag2:jdp2) fish are resistant to dexamethasone. (A) Representative fluorescent images of thymuses from 8-d-old stable transgenic zebrafish larvae exposed to dexamethasone (25 µg/ml) or DMSO control, from day 5 postfertilization (dpf). Bar, 0.1 mm. (B) Quantification of thymic fluorescence in 8-d-old stable transgenic zebrafish larvae exposed to 25 µg/ml dexamethasone or DMSO control from 5 dpf. Values are expressed as a percentage of thymic fluorescence in DMSO control treated zebrafish, and P values were calculated using two-tailed Student’s t test. Findings were validated in three independent experiments.