Figure 2.
Stick or click approaches for decoration of virus-like particle (VLP) vaccines. Non-covalent decoration of VLPs is represented by nickel-affinity or biotin/streptavidin decoration (pink). Covalent decoration of VLPs is represented in gray. We illustrate unnatural amino acid incorporation via global incorporation of azidohomoalanine in the VLP, sortase ligation, or split intein trans-splicing. The antigen is represented in gold; not to scale.
