Table 2.

Correlations between diffusion metrics in major white matter (WM) tracts and the cognitive test score.

Fiber tract	FA value vs. MoCA score		MD value vs. MoCA score		LDH value vs. MoCA score
	CC	P value	CC	P value	CC	P value
LATR	0.452	0.026 (0.045)	−0.579	0.003 (0.031)	0.566	0.004 (0.032)
RATR	0.512	0.011 (0.032)	−0.496	0.013 (0.032)	0.433	0.034 (0.052)
RCST	0.337	0.107 (0.120)	−0.447	0.028 (0.045)	0.392	0.058 (0.073)
FM	0.493	0.014 (0.032)	−0.496	0.013 (0.032)	0.548	0.006 (0.032)
LIFOF	0.465	0.022 (0.041)	−0.503	0.012 (0.032)	0.362	0.082 (0.099)
RIFOF	0.501	0.013 (0.031)	−0.517	0.009 (0.031)	0.401	0.052 (0.068)
LILF	0.533	0.007 (0.032)	−0.474	0.019 (0.038)	0.328	0.118 (0.127)
LSLF	0.451	0.027 (0.045)	−0.491	0.014 (0.032)	0.065	0.762 (0.763)
LUF	0.407	0.048 (0.066)	−0.525	0.008 (0.031)	0.346	0.098 (0.113)
RUF	0.420	0.041 (0.059)	−0.497	0.013 (0.032)	0.179	0.403 (0.417)

LATR, left anterior thalamic radiation; RATR, right anterior thalamic radiation; RCST, right corticospinal tract; FM, forceps minor; LIFOF, left inferior fronto-occipital fasciculus; RIFOF, right inferior fronto-occipital fasciculus; LILF, left inferior longitudinal fasciculus; LSLF, left superior longitudinal fasciculus; LUF, left uncinate fasciculus; RUF, right uncinate fasciculus; CC, correlation coefficient. The numbers in the bracket indicate the corrected P values. Here, the false-discovery rate (FDR) correction is applied for multiple comparisons (n = 30). Bold numbers indicate a corrected P value < 0.05. It is noteworthy that all three diffusion parameter values in LATR and FM were significantly correlated with the cognitive test score.