Table 1. Protein interactors of Wdr92.
| Drosophila gene | Protein accession number | Human protein | Notes | Fold enrichment a | Human interaction reported b |
|---|---|---|---|---|---|
| R2TP/prefoldin-like complex | |||||
| spaghetti | Q9V3E9 | RPAP3 | R2TP | 2.06 (0.0002) | + |
| CG5792 | Q9VK57 | PIH1D1 | R2TP | 2.22 (0.0044) | + |
| uri | Q9W148 | URI | PFDL | 246.45 (4.51 × 10−7) | + |
| l(3)01239 | M9PF40 | PFDN2 | PFDL | 19.81 (4.4 × 10−9) | + |
| CG7770 | M9PD09 | PFDN6 | PFDL | 26.39 (2.8 × 10−6) | + |
| l(2)35Cc | Q9VJP9 | UXT | PFDL | 22.85 (0.0002) | + |
| CG15863 | Q4QQ01 | PDRG1 | PFDL | 291.12 (4.54 × 10−7) | + |
| pp1-13C | Q05547 | PP1α | Uri interactor | 2.87 (0.0001) | + |
| DNAAFs | |||||
| dtr | Q8INT5 | DNAAF1 | PCD | 1.75 (0.0042) | − |
| CG18472 | Q9VBA1 | SPAG1 | PCD | 2.04 (0.0002) | − |
| Axonemal dynein chains | |||||
| kl-5 | Q5LJN5 | DNAH17 | HC OADβ, PCD | 8.66 (0.0012) | − |
| kl-3 | A8Y5B7 | DNAH8 | HC OADγ, PCD | 4.49 (0.0004) | − |
| Dhc62B | Q7KVA7 | DNAH12 | HC IAD, monomeric | 14.12 (0.0119) | − |
| Dhc98D | E1JJ04 | DNAH10 | HC IAD, dimeric | 1.72 (0.0011) | − |
| CG9313 | Q8MSJ9 | DNAI1 | IC ODA, PCD | 2.61 (0.0002) | − |
| CG10859 | Q9VJY4 | DNAI2 | IC ODA, PCD | 3.11 (0.0006) | − |
| CG31802 | Q8T415 | Centrin | IC IDA, monomeric | 2.49 (0.0426) | − |
| CG8407 | A1Z8T9 | DNAL4 | LC ODA | 6.87 (0.0067) | − |
| Other | |||||
| CG3121 | Q9W1D3 | RSPH4A/6A | Radial spoke, PCD | 2.03 (0.0094) | − |
| CG5458 | Q9VK29 | RSPH1 | Radial spoke, PCD | 3.29 (0.0049) | − |
| Zipper | Q59E58 | MYH9/10 | Myosin HC | 4.48 (0.0403) | + |
| CG34107 | Q0KI89 | PIERCE1 | LR asymmetry (mouse) | 1.94 (0.0211) | − |
| CG15128 | A1ZBP5 | TTC25 | Dynein docking, PCD | 3.88 (0.0248) | − |
LC, light chain; PFDL, prefoldin-like complex.
a
Fold difference Wdr92 AP versus control AP (p-value).
b
Homologous interaction reported for human WDR92 in cultured nonmotile ciliated cells (Choi et al., 2011).