Table 3.
Summary of the Published Cases of Idiopathic Diffuse Pulmonary Ossification.
| Case No. | Age, years | Sex | Past medical history | Family history | Smoking history | Environmental / occupational exposures | Pulmonary function test, % predicted | Reference No. |
|---|---|---|---|---|---|---|---|---|
| 1 | 34 | M | Intermittent hemoptysis | Not mentioned | 10 pack-years | Never | FVC: 109%, FEV1: 87%, DLCO: 72% | 5 |
| 2 | 29 | M | Pneumothorax | Father: Dendriform pulmonary ossification | Not mentioned | Not mentioned | Not mentioned | 9 |
| 3 | 43 | M | Allergic rhinitis/ Asthma/ Diabetes mellitus/ Coronary atherosclerotic heart disease | Not mentioned | Never | Never | "Lung volumes and DLCO have declined slightly over 14 years" | 10 |
| 4 | 51 | M | None | Not mentioned | Not mentioned | Never | "Normal except for an isolated reduction in the transfer factor (73% predicted)" | 11 |
| 5 | 26 | M | Cleft lip and palate/ Chronic sinusitis | None | Never | Never | "Normal" | 12 |
| 6 | 32 | M | Pneumonia | Not mentioned | Never | Never | VC: 93%, FVC: 82%, FEV1: 71%, DLCO: 102% | 13 |
| 7 | 47 | M | Pneumothorax | Not mentioned | Not mentioned | Exposure to methylmethacrylate, quartz cristobalite, chrome cobalt, alginates, asbestos and silica as a dental technician | "Normal" | 14 |
| 8 | 49 | M | None | Not mentioned | Never | Not mentioned | "A slow and progressive decline in pulmonary function" | 15 |
| 9 | 58 | M | Left renal artery stenosis/ Ischemic stroke | Not mentioned | Not mentioned | Never | Not mentioned | 16 |
| 10 | 43 | M | None | Not mentioned | Never | Never | VC: 110%, FVC: 99%, FEV1: 92%, DLCO: 71% | 17 |
| 11 | 33 | M | Pneumothorax/ Asthma | Not mentioned | Never | Not mentioned | Not mentioned | 18 |
| 12 | 53 | M | Pneumothorax | Not mentioned | Not mentioned | Not mentioned | Not mentioned | 19 |
| 13 | 26 | M | Pneumothorax | Father: Similar lung condition in his 30s with computed tomography (CT) images | Never | Never | "Normal" (FEV1: 91%) | 20 |
| 14 | 47 | F | Hypoplasia and deformity of the middle fingers/ Diabetes mellitus/ Schizophrenia | Father: Multiple small high density nodules by CT | Never | Never | VC: 101%, FEV1: 71% | 21 |
In addition to the case with "idiopathic" in the publication, the possible cases were included. Some old publications which have only abstracts with little information of the cases on the PubMed were excluded. Not mentioned: No available information in the publication, VC: vital capacity, FVC: forced vital capacity, FEV1: forced expiratory volume in one second, DLCO: diffusing capacity of the lung for carbon monoxide