Figure 3.

Associations between connectivity and behavioral measures: Behavioral/clinical relevance of the connectivity from the left mPFC to the right amygdala: significant association of this connectivity (averaged across all task blocks) with (A) subjective fear rating across all participants (R² = 0.10, P = 0.0016, 95% CI = [0.02,0.24]), (B) Eating Disorder Examination score (EDE) in anorexia nervosa (R² = 0.32, P = 0.0029, 95% CI = [0.05,0.62]), and (C) Hamilton Anxiety Scale (HAMA) in anorexia nervosa (R² = 0.29, P = 0.0055, 95% CI = [0.03,0.59]). No other significant associations were found between any significant connection and any of these scores, as well as with scales measuring obsessive and compulsive eating disorder and BDD symptoms (Yale-Brown-Cornell Eating disorder scale and the body dysmorphic disorder version of the Yale-Brown Obsessive-Compulsive scale, respectively) and the Montgomery-Asberg Depression Rating Scale (MADRS).