Table 4.
Percentages of cells in each phase of cell cycle (%).
| DPCs |
ORSCs |
|||||
|---|---|---|---|---|---|---|
| G1 phase | S phase | G2/M phase | G1 phase | S phase | G2/M phase | |
| Control | 65.00 ± 1.32 | 16.44 ± 1.12 | 17.85 ± 1.72 | 64.83 ± 2.60 | 13.75 ± 1.14 | 20.58 ± 2.05 |
| EGCG | 50.20 ± 1.83### | 23.35 ± 2.30## | 24.98 ± 2.40# | 56.53 ± 3.39# | 23.95 ± 2.85## | 18.71 ± 1.76 |
| Cyclopamine | 69.72 ± 2.87 | 12.21 ± 1.52 | 17.65 ± 1.76 | 66.34 ± 2.20 | 10.36 ± 1.09 | 22.14 ± 2.46 |
| EGCG+ Cyclopamine | 64.51 ± 3.14∗∗ | 16.86 ± 1.70∗ | 18.01 ± 1.71∗ | 63.13 ± 4.05 | 15.28 ± 1.90∗ | 20.47 ± 2.44 |
| GANT61 | 72.98 ± 2.36 | 12.31 ± 1.69 | 13.47 ± 1.94 | 66.10 ± 2.37 | 10.38 ± 1.60 | 22.35 ± 2.61 |
| EGCG+ GANT61 | 65.66 ± 2.37∗∗∗ | 17.38 ± 2.19∗ | 16.76 ± 1.78∗∗ | 63.87 ± 1.22∗ | 14.71 ± 1.77∗∗ | 20.75 ± 2.18 |
| LY2940002 | 70.24 ± 1.52 | 11.84 ± 1.57 | 17.19 ± 1.85 | 68.20 ± 2.87 | 10.21 ± 1.82 | 20.80 ± 2.32 |
| EGCG+ LY2940002 | 56.06 ± 2.98∗ | 18.56 ± 1.91∗ | 24.50 ± 1.09 | 65.16 ± 3.45∗ | 15.12 ± 1.73∗ | 18.84 ± 3.77 |
The results are presented as mean ± SD. #p < 0.05, ##p < 0.01, ###p < 0.001 compared with the Control group. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 compared with the EGCG group.