FIGURE 1.

Phylogenetic trees of XoxF and XoxF-like proteins translated from the genomes (total of 34) and genomic bins (total of 21) of Methylophilaceae originating from across the globe (A) and from genomes of non-Methylophilaceae (total of 30), all from Lake Washington sediment (B), reveal differential distribution of XoxF4 and XoxF5 types among bacteria. Bar, % amino acid divergence. Number of sequences in each cluster is indicated. Clade classifications are in accordance with previously published classifications (Chistoserdova, 2011; Keltjens et al., 2014; Good et al., 2016). Sequences clustering outside of these clades are designated as unclassified.