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. 2018 Jun 26;9:1395. doi: 10.3389/fmicb.2018.01395

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Copyright © 2018 Tsitsopoulou, Posso, Vale, Bebb, Johnson and White.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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VIPcheck™ plates containing itraconazole at concentration of 4 mg/l (Well 1; top left), voriconazole at a concentration of 2 mg/l (Well 2; top right), posaconazole at a concentration of 0.5 mg/l (Well 3; bottom left) and a control well containing only RPMI agar (Well 4; bottom right) for (A) a fully azole sensitive environmental strain of A. fumigatus (64a); (B) a pan-azole resistant environmental strain of A. fumigatus (302w1) and (C) an itraconazole resistant environmental strain of A. fumigatus (BR8320) showing sporadic growth in the presence of voriconazole and posaconazole.