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. 2018 Jul 3;38(4):BSR20180532. doi: 10.1042/BSR20180532

Figure 3. IL-6-induced JunB expression contributes to EMT changes in UM cells.

Figure 3

(A) Immunofluorescence analysis of Vimentin in IL6/C918 and C918 cells. (B) The protein levels of TJP1 and Vimentin in C918 and OCM1A cells at different time points during IL-6-induced transformation. (C) Enrichment changes of AP-1 family members in IL6/C918 versus C918, based on RNA-seq data. (D) The mRNA levels of c-Jun, JunB, and c-Fos in IL6/C918 and C918 cells; *P<0.05; **P<0.01. (E) The protein levels of JunB and c-Jun in C918 cells at different time points during IL-6-induced transformation. (F) The protein levels of JunB, c-Jun, TJP1, and Vimentin in IL6/C918 and C918 cells with the knockdown of JunB or c-Jun.