Figure S3.

Oxygen binding fractional saturation curves for purified recombinant HbA and HbF.

DeoxyHb was titrated with oxygen for rHbA (red circles) and rHbF (blue circles). Data was fitted to a sigmoidal curve based on the Monod-Wyman-Changeux model of the allosteric binding of oxygen to Hb (solid lines). Dotted lines represents the data for the oxygen binding to Hb following PEGylation (red for rHbA and blue for rHbF).

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