Table I.
Statistical test cut-off criterion |
Sensitivity 95% CI |
Specificity 95% CI |
PPV 95% CI |
NPV 95% CI |
Positive LR 95% CI |
Diagnostic value | Negative LR 95% CI |
Diagnostic value | ||
---|---|---|---|---|---|---|---|---|---|---|
OS | < 2 dB SPL |
TEOAEs | 87% 81.05-92.25 |
67% 58.45-75.65 |
77% 69.71-82.84 |
81% 72.45-88.4 |
2.69 2.07-3.49 |
Small | 0.19 0.12-0.29 |
Moderate |
DPOAEs | 95% 89.38-97.84 |
64% 55.16-71.77 |
71% 64.12-77.99 |
93% 85.41-96.99 |
2.61 2.09-3.27 |
Small | 0.08 0.04-0.17 |
Large | ||
< 1 dB SPL |
TEOAEs | 54% 45.35-61.78 |
91% 84.56-95.45 |
88% 79.61-93.88 |
62% 54.05-68.64 |
6.00 3.35-10.75 |
Moderate | 0.51 0.43-0.61 |
Very small | |
DPOAEs | 75% 66.98-81.93 |
88% 80.78-92.80 |
87% 79.42-92.25 |
77% 68.88-83.06 |
6.09 3.81-9.74 |
Moderate | 0.29 0.21-0.38 |
Small | ||
LFS | < 2 dB SPL |
TEOAEs | 83% 76.54-88.99 |
63% 54.05-71.94 |
74% 66.85-80.52 |
75% 65.67-83.3 |
2.28 1.78-2.91 |
Small | 0.26 0.18-0.38 |
Small |
DPOAEs | 89% 82.72-94.03 |
65% 56.21-72.96 |
71% 63.77-78.12 |
86% 77.84-92.21 |
2.55 2.01-3.23 |
Small | 0.16 0.10-0.27 |
Moderate | ||
< 1 dB SPL |
TEOAEs | 51% 43.05-59.57 |
90% 83.32-94.77 |
87% 77.63-92.83 |
60% 52.38-67.07 |
5.18 2.96-9.05 |
Moderate | 0.54 0.45-0.64 |
Very small | |
DPOAEs | 60% 50.99-67.75 |
87% 79.89-92.44 |
84% 75.32-90.57 |
65% 57.67-72.67 |
4.62 2.87-7.44 |
Small | 0.46 0.38-0.57 |
Small | ||
HFS | < 2 dB SPL |
TEOAEs | 88% 80.88-92.60 |
51% 41.62-59.98 |
67% 59.27-73.50 |
78% 67.80-86.94 |
1.78 1.47-2.16 |
Very small | 0.24 0.15-0.39 |
Small |
DPOAEs | 97% 91.69-99.08 |
50% 40.20-58.97 |
66% 58.76-73.24 |
94% 84.30-98.21 |
1.92 1.60-2.30 |
Very small | 0.07 0.03-0.18 |
Large | ||
< 1 dB SPL |
TEOAEs | 49% 40.27-57.58 |
75% 66.54-82.60 |
69% 58.88-78.07 |
57% 48.49-64.31 |
1.96 1.38-2.81 |
Very small | 0.68 0.56-0.82 |
Very small | |
DPOAEs | 78% 69.41-85.07 |
74% 65.11-81.56 |
75% 66.17-82.19 |
77% 68.40-84.53 |
2.99 2.18-4.11 |
Small | 0.30 0.21-0.43 |
Small |
OS = mean suppression for all frequencies, LFS = mean suppression for lower frequencies (1-2 kHz), HFS = mean suppression for higher frequencies (2.8-4 kHz for TEOAEs and 2.8-6 kHz for DPOAEs), PPV = positive predictive value, NPV = negative predictive value, LR = likelihood ratio.