Fig. 2.

A schematic diagram of the decline of cerebellar function and the concept of “restorable stage” and “cerebellar reserve.” Proper therapies could restore cerebellar function in patients, whose cerebellum is at the “restorable stage,” meaning the presence of a sufficient reserve of cerebellar function. After a given threshold of neuronal loss or dysfunction in the cerebellar circuitry, cerebellar function cannot be restored anymore due to severe loss of computational capacity of the remaining cerebellar modules