Table 1.
Effects of adiponectin on colonic expression of apoptosis relative genes in mice
| Item | Cont | DSS | Adiponectin | DSS + Adiponectin |
|---|---|---|---|---|
| Day 4 | ||||
| p53 | 1.00 ± 0.13ab | 1.34 ± 0.17a | 0.85 ± 0.07b | 1.23 ± 0.12a |
| Bcl-2 | 1.00 ± 0.12 | 0.92 ± 0.13 | 0.96 ± 0.12 | 0.91 ± 0.09 |
| Bax | 1.00 ± 0.09b | 1.65 ± 0.16a | 0.94 ± 0.06b | 1.55 ± 0.13a |
| Day 7 | ||||
| p53 | 1.00 ± 0.13b | 1.56 ± 0.14a | 1.02 ± 0.09b | 1.27 ± 0.13ab |
| Bcl-2 | 1.00 ± 0.13 | 1.01 ± 0.13 | 1.23 ± 0.16 | 1.28 ± 0.20 |
| Bax | 1.00 ± 0.16bc | 1.87 ± 0.13a | 0.74 ± 0.13c | 1.40 ± 0.13b |
| Day 10 | ||||
| p53 | 1.00 ± 0.09c | 1.76 ± 0.16a | 0.84 ± 0.18c | 1.44 ± 0.14b |
| Bcl-2 | 1.00 ± 0.05b | 0.56 ± 0.08c | 1.43 ± 0.09a | 0.53 ± 0.11c |
| Bax | 1.00 ± 0.11b | 1.92 ± 0.11a | 0.68 ± 0.08c | 1.37 ± 0.16b |
Data are presented as mean ± SEM. The values having different superscript letters were significantly different (P < 0.05; n = 10)