Table 3.

Model input parameters used in company’s model

Variable	Value per patient	Source	EAC critique
Theatre staff costs: Memokath-051	£1160	[35] Included: anaesthetist, surgeon, band 6 and band 5 scrub, band 5 anaesthetist, band 2 circulating, band 2 porter, band 6 and band 5 recovery	Duration of procedure: procedure time of 4 h and a theatre time (all staff present apart from the surgeon) of 4.5 h. The EAC judged this to be too long based upon information provided by the company and experts Recovery staff: Cost of a band 5 and band 6 recovery staff included appropriately given that no additional hospital stay was included following insertion Staff costs: Staff costs per hour did not include national insurance and superannuation costs. These are directly related to earnings and should be included
Theatre staff costs: double-J stent	£1160	[35] Included: anaesthetist, surgeon, band 6 and band 5 scrub, band 5 anaesthetist, band 2 circulating, band 2 porter, band 6 and band 5 recovery	Duration of procedure: as above Recovery staff: as above Staff costs: as above
Theatre consumable costs: Memokath-051	£1874	[35] Included: device, cystoscopy pack, instilagel, 20-ml syringe, sensor guide wire, passport, jug, pink needle, green needle	The company’s consumable cost includes a device cost of £1630. This is lower than the current list price of £1690 reported in the company’s submission
Theatre consumable costs: double-J stent	£109	[35] Included: device, cystoscopy pack, instilagel, 20-ml syringe, sensor guide wire	The EAC deems this value appropriate based upon the AUH data [35]
Procedure code/surgery tariff: Memokath-051	£34	[35]	The EAC judges the inclusion of a tariff cost is inappropriate for analysis from the NHS and PSS perspective and excluded this parameter from its analysis
Procedure code/surgery tariff: double-J stent	£407	[35]	As above
6-month follow-up costs: Memokath-051	£143	[35] Included: x-ray abdomen, nuclear medicine renogram and 2 outpatient appointments over 1 year. 1 year cost divided by 2 to estimate the 6 month cost	The EAC deems this value appropriate based upon the AUH data. However, using national sources for unit costs would increase the cost [40]
6-month follow-up costs: double-J stent	£100	No source provided	It is unclear how this cost was derived and is not included within the AUH data, thus is deemed inappropriate
Risk of unplanned exchange: Memokath-051	£945	Calculated as 25% of the undiscounted pathway-related cost for 2.5 years	The EAC judges that this cost has been applied incorrectly given that it was applied to the total per patient cost over 2.5 years as opposed to the insertion cost only
Risk of unplanned exchange: double-J stent	£0	Zero as no risk factor for complications	Given that double-J stents undergo planned replacement, this is considered appropriate and is in line with clinical evidence [7]

AUH Aintree University Hospital, EAC External Assessment Centre, NHS National Health Service, PSS Personal Social Services