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. 2018 May 8;293(26):10202–10219. doi: 10.1074/jbc.RA118.002971

Figure 2.

Figure 2.

Growth of HCC70 cells in the presence of enzymatically degraded XylNap-primed CS/DS from HCC70 cells. The growth of HCC70 cells after 96 h of treatment with XylNap-primed GAGs degraded with heparinase II and III (Hep; black), heparinase II and III and chondroitinase ABC (Hep + ChABC; gray), heparinase II and III and chondroitinase AC-I and -II (Hep + ChAC; blue), or heparinase II and III and chondroitinase B (Hep + ChB; white). The concentrations of the GAGs administered to the cells were de facto lower than the indicated concentrations, as the indicated concentrations correspond to the concentrations of the GAGs before enzymatic degradation. The data points are the means ± S.D., in which n = 3. UT, untreated.