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. 2018 May 14;293(26):10303–10313. doi: 10.1074/jbc.RA118.002087

Figure 3.

Figure 3.

Fluorescence COM, calculated as reported under “Experimental procedures,” plotted versus pH, for WT (black circles) and G118V (gray diamonds) profilin-1. This analysis reveals the transition from folded to acid-unfolded protein as a red shift (i.e. an increase in COM) occurring at low pH.