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. 2018 May 10;293(26):10353–10362. doi: 10.1074/jbc.RA118.002889

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© 2018 Abou El Hassan et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 2. — Histone acetylation is enriched near gene promoters. A, the percentage of IFNγ-induced H3ac or H4ac marked sites versus randomly generated controls at proximal (≤5 kb) or distal (>5 kb) sites relative to the TSS of known genes. B, histograms show the percentages of total, constitutive, and induced H3ac (left) and/or H4ac (right) at proximal (≤5 kb) and distal (>5 kb) sites of ISGs, separated into isolated or dual (overlapping H3ac/H4ac) acetylation. The total number of sites in each category is indicated below the bars. Const., constitutive; Ind., induced.