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. 2018 Jul 3;49:54. doi: 10.1186/s13567-018-0547-5

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Expression of intestinal epithelial cell lineage-specific genes in bovine small intestinal crypts and enteroids. A–H Heat maps showing the relative expression levels (log₂ transcripts/million reads, TPM) of cell lineage-specific genes: A intestinal stem cell; B transit-amplifying (TA) cells, early enterocyte precursor (ECepr) cells, late enterocyte precursor (EClpr) cells; C enterocytes; D SL, secretory lineage; E goblet cells; F Paneth cells; G enteroendocrine precursor (EEpr) cells, enteroendocrine (EE) cells, enteroendocrine cell derived hormones; H tuft cells. P, enteroid passage number; ***α-defensin genes are not represented in the bovine genome. I Expression of POU2F3 in mRNA-seq data sets derived from distinct regions of the sheep gastrointestinal tract [59]. N, neonate; L1, 1 week old lamb; L8, 8 week old lamb; A, adult.