Fig. 3.

Two-sample logo of the 3 residue positions at the a N-terminus and b C-terminus of the A-cell epitopes and non-epitopes. Enriched label represents the positive dataset whereas depleted label represents the negative dataset. In a two-sample logo, the height of a symbol at a residue position is proportional to the difference in symbol frequency between the positive and the negative datasets at that residue position. In the case of A-cell epitopes (as positives) and non-epitopes (as negatives), R is a preferred amino acid at terminal positions apart from I and V. The symbol colors are in accordance with the WebLogo default color scheme provided by the server available at http://www.twosamplelogo.org/cgi-bin/tsl/tsl.cgi. In the default WebLogo color scheme, residues G, S, T, Y and C appear in green color, N and Q are colored purple, K, R and H are depicted in blue, D and E are drawn red and P, A, W, F, L, I, M and V are shaded black