Table 1.

Summary of the yeast two-hybrid results from previous publications [21, 22]

Name	Amino-acid sequence	β3-EN binding
β1CT:	-KLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNPKYEGK	-(a)
β2CT:	-KALIHLSDLREYRRFEKEKLKSQWN-NDNPLFKSATTTVMNPKFAES	-
β3CT:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT(c)	+
β3CT-Δ762:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRG	+
β3CT-Δ761:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYR	+
β3CT-Δ760:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITY	+
β3CT-Δ759:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNIT	-
β3CT-Δ755:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTF	-
αIIb/β3CT:	-KVGFFKRNRPPLEEDDEEGQNITYRGT	-
β1/β3CT1:	-KLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNITYRGT	+
β1/β3CT2:	-KLLMIIHDRREFAKFEKEKMNAKWDTGENPIYKSAVTTVVNITYEGK	+
β3/β1CT1:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNPKYEGK	-
β3/β1CT2:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNPKYRGT	-
β3CT-I/P:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNPTYRGT	-
β3CT-Y/F:	-KLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITFRGT	+
Binding core:		xNITY(b)

^(a)The interactions between β3-endonexin (β3-EN) and the original and chimeric integrin β CTs were defined by arbitrary units (AU) of β-Galactosidase as described in the publications. (Positive interactions (+): AU > 5; negative interactions (−): AU < 5)

^(b)The “x” represented undetermined amino acids (number and residues)

^(c)Amino acids from the integrin β3 CT were shown in boldface