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. 2018 Jul 3;18:133. doi: 10.1186/s12872-018-0875-4

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — ACE staining in myocardial cells of mice from four experimental groups. a & b: CIH group; c & d: ARB group; e & f:blank control group; g & h: air control group. Immunohistochemistry was performed on the cardiac apex sections as described in Materials and methods. CIH and ARB groups showed highest ACE staining in CIH group followed by ARB group compared with the two control groups although this reduction did not reach statistical significance. Magnification: a, c, e and g: 100×; b, d, f and h: 400×. scale bar,100 μm