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. 2018 Jun 26;9:603. doi: 10.3389/fphar.2018.00603

Table 1.

Demographic and clinical data for neonates in this study.

Variable Modeling group Median (range)
Number of patients (male/female) 80 (54/26) /
Number of observations (trough /peak) 165 (75/90) /
Postnatal age (PNA), days 32.3 ± 24.1 24 (4–126)
Gestational weeks (GA), weeks 34.7 ± 4.31 34 (25.7–41.1)
Postmenstrual age (PMA), weeks 39.4 ± 3.60 40.0 (29–47.1)
Weight, kg 2.87 ± 0.89 2.74 (1.4–5.6)
Height, cm 46.8 ± 4.72 47 (37–65)
Serum creatinine, μmol/L 23.2 ± 10.4 28.3 (5.85–61.6)
Blood urea nitrogen, mmol/L 4.96 ± 3.89 4.1 (0.4–28.5)
Total protein, g/L 48.6 ± 7.38 48.2 (33–67.6)
Albumin, g/L 32.4 ± 5.49 32 (21.6–46.8)
Aspartate aminotransferase, U/L 43.6 ± 85.1 18 (3–575)
Glutamic-pyruvic transaminase, U/L 77.6 ± 109 41 (9-696)
Dosage, mg 45 ± 16.4 42 (20–105)
Trough concentration, mg/L 11.2 ± 7.92 9.15 (3.14–42.9)
Peak concentration, mg/L 22.3 ± 11.0 20.3 (4.09–51.9)