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. 2018 Jul 3;49:55. doi: 10.1186/s13567-018-0551-9

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effect of endosome alkalization on CRCoV infection. A Analysis of inhibitors effect on CRCoV entry, cells were pretreated with inhibitors, infected in presence of them and incubated for 1 h before they were washed off and fixed. CRCoV virions are presented in green, blue denotes DNA and red represents actin, each image is a single confocal plane while B represents maximum projections of their axial planes. Scale bar 10 µm.