Fig. 5.

Ablation of β-catenin in macrophages attenuates mac­rophage proliferation in the kidneys with UUO nephropathy. a, b Representative images for costaining of F4/80 and Ki67 (a) and quantitative analysis for Ki67- and F4/80-positive macrophages in kidney tissues (b). Arrows indicate costaining-positive macrophages. * p < 0.05 versus β-catenin+/+ sham control, n = 5; ^#p < 0.05 versus β-catenin+/+ control littermates after UUO, n = 5. c FACS analysis showing macrophage proliferation for macrophages from UUO kidneys. * p < 0.05 versus macrophages from Mac-β-catenin+/+ UUO kidneys, n = 4. UUO, unilateral ureter obstruction.