Table 1.
Aspects of cell mechanics | Cell type | Magnitude | Tool/Technique | References |
---|---|---|---|---|
Stiffness | Fibroblasts Fibroblasts Vascular endothelial cells Vascular smooth muscle cells Rat ASM(airway smooth muscle)cells |
0.02 N/m 0.02 N/m 0.03–0.04 N/m 0.09–0.88 N/m 0.099 N/m |
Mcropipette Magnetic twisting cytometer |
[231] [232] |
Elastic modulus | Cancer MCF-7 cell Osteoblasts Skeletal muscle cells Cardiocytes Erythrocytes Leukocytes Fibroblasts Endothelial cells Outer hair cells |
0.95 – 1.19 kPa 0.3–20 kPa 8–45 kPa 90–110 kPa 14–33 kPa 0.2–1.4 kPa 0.6–12 kPa 0.2–2 kPa 2–4 kPa |
Atomic force microscopy |
[233] [234] [235,236] [237] [238,239] [240] [241,242] [243] [244] |
Viscoelasticity | Cytoplasm | 210 Pa s 2000 Pa s |
Magnetic bead microrheology | [245] [246] |
Cell adhesion force | Human cervical carcinoma cell Epithelial cells Murine fibroblast cells Rat cardiac fibroblast |
19–204 nN 100 nN 300–400 nN 10 nN |
Atomic force microscopy High-speed centrifugation technique Manipulation force microscope Traction force microscopy |
[247] [248] [249] [250] |
Cell traction forces | Fibroblasts Fish keratocytes |
100 nN 20 nN |
Microcantilevers micro pads Flexible substrate |
[251] [58] |
Shear stress | Endothelial cells Bovine aortic endothelial cells Human umbilical vein endothelial cells |
1–15 dyn/cm2 10 dyn/cm2 1–3 dyn/cm2 |
Microfluidics | [252-254] [255] [256] |