Table 2.

Association of p53 over expression categories with clinic pathologic parameters of head and neck Squamous cell carcinoma

	n (%)					P value	Power of test (%)
	≤ 10% (n = 43)	11–50% (n = 23)	51–70% (n = 23)	> 70% (n = 32)	Total (n = 121)
Age group (years)
≤ 30	3 (7)	0 (0)	1 (4.3)	1 (3.1)	5 (4.1)	0.502	37.12
31–50	23 (53.5)	8 (34.8)	10 (43.5)	17 (53.1)	58 (47.9)
> 50	17 (39.5)	15 (65.2)	12 (52.2)	14 (43.8)	58 (47.9)
Gender
Male	36 (83.7)	15 (65.2)	16 (69.6)	22 (68.8)	89 (73.6)	0.299	33.12
Female	7 (16.3)	8 (34.8)	7 (30.4)	10 (31.3)	32 (26.4)
Depth of invasion (cm)
< 2	36 (83.7)	17 (73.9)	23 (100)	26 (81.3)	102 (84.3)	0.056	54.7
≥ 2	7 (16.3)	6 (26.1)	0 (0)	6 (18.8)	19 (15.7)
Nodal stage
N0	26 (60.5)	16 (69.6)	12 (52.2)	13 (40.6)	67 (55.4)	0.258	65.64
N1	8 (18.6)	1 (4.3)	3 (13)	6 (18.8)	18 (14.9)
N2a	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
N2b	9 (20.9)	5 (21.7)	7 (30.4)	11 (34.4)	32 (26.4)
N2c	0 (0)	0 (0)	1 (4.3)	2 (6.3)	3 (2.5)
N3	0 (0)	1 (4.3)	0 (0)	0 (0)	1 (0.8)
Histological subtypes
Non-keratinizing	3 (7)	1 (4.3)	4 (17.4)	10 (31.3)	18 (14.9)	0.100	71.32
Keratinizing	28 (65.1)	15 (65.2)	12 (52.2)	14 (43.8)	69 (57)
Non-keratinizing with maturation	12 (27.9)	7 (30.4)	7 (30.4)	8 (25)	34 (28.1)
Histologic grade
Grade-I	13 (30.2)	11 (47.8)	5 (21.7)	4 (12.5)	33 (27.3)	0.065	74.37
Grade-II	24 (55.8)	11 (47.8)	13 (56.5)	25 (78.1)	73 (60.3)
Grade-III	6 (14)	1 (4.3)	5 (21.7)	3 (9.4)	15 (12.4)
Perineural invasion
Not present	39 (90.7)	22 (95.7)	21 (91.3)	23 (71.9)	105 (86.8)	0.051	69.81
Present	4 (9.3)	1 (4.3)	2 (8.7)	9 (28.1)	16 (13.2)

Chi square test was applied

P-value ≤ 0.05 considered as significant