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. Author manuscript; available in PMC: 2019 Apr 5.
Published in final edited form as: Cell. 2018 Apr 5;173(2):371–385.e18. doi: 10.1016/j.cell.2018.02.060

KEY RESOURCES TABLE.

REAGENT or RESOURCE SOURCE IDENTIFIER
Antibodies
Bacterial and Virus Strains
Biological Samples
Chemicals, Peptides, and Recombinant Proteins
Critical Commercial Assays
Deposited Data
Public MC3 MAF Ellrott et al. https://gdc.cancer.gov
Clinical Data Liu et al. https://gdc.cancer.gov
Target Drug Database - Phial Van Allen et al., 2014 https://github.com/vanallenlab/2017-tcga-mc3_phial
DEPO Sun et al. http://depo-dinglab.ddns.net
OncoKB Chakravarty et al., 2017 http://oncokb.org
Mutation Validation Ng et al. 2018 N/A
Experimental Models: Cell Lines
Experimental Models: Organisms/Strains
Oligonucleotides
Recombinant DNA
Software and Algorithms
20/20+ Tokheim et al., 2016b https://github.com/KarchinLab/2020plus
MutSig2CV Lawrence et al., 2014 http://archive.broadinstitute.org/cancer/cga/mutsig_run
MuSiC2 Dees et al., 2012 https://github.com/ding-lab/MuSiC2
OncodriveCLUST Tamborero et al., 2013a http://bg.upf.edu/group/projects/oncodrive-clust.php
OncodriveFML Mularoni et al., 2016 http://bg.upf.edu/oncodrivefml/home
ActiveDriver Reimand and Bader, 2013 http://individual.utoronto.ca/reimand/ActiveDriver/
CompositeDriver Liu et al. https://github.com/khuranalab/CompositeDriver
HotMAPS Tokheim et al., 2016a https://github.com/KarchinLab/HotMAPS
CHASM Carter et al., 2009 http://www.cravat.us/CRAVAT/
VEST Carter et al., 2013 http://www.cravat.us/CRAVAT/
e-Driver Porta-Pardo and Godzik, 2014 https://github.com/eduardporta/e-Driver
CanDrA Mao et al., 2013 http://bioinformatics.mdanderson.org/main/CanDrA
HotSpot3D Niu et al., 2016 (https://github.com/ding-lab/hotspot3d)
3DHotSpots.org Gao et al., 2017 http://3dhotspots.org
e-Driver3D Porta-Pardo et al., 2015 http://github.com/eduardporta/e-Driver
DriverNET Bashashati et al., 2012 http://compbio.bccrc.ca/software/drivernet/
OncoIMPACT Bertrand et al., 2015 https://github.com/CSB5/OncoIMPACT
MutationAssessor Reva et al., 2011 http://mutationassessor.org/r3/
SIFT Ng and Henikoff, 2002 http://sift.jcvi.org
PolyPhen2 Adzhubei et al., 2013 http://genetics.bwh.harvard.edu/pph2/
fathmm Shihab et al., 2013 http://fathmm.biocompute.org.uk
transFIC Gonzalez-Perez et al., 2012 http://bg.upf.edu/transfic/home
CTAT-score This Paper https://gdc.cancer.gov
MSIsensor Niu et al., 2013 https://github.com/ding-lab/msisensor
Other