Table 1.
Author | Exercise dose | Subtype EV | Preanalytical phase | Collection time | Response |
---|---|---|---|---|---|
Harrison et al. [76] | Cycling for 90 min at 70% VO2peak followed by ten 1 min sprints interspersed with 1 min of recovery in young, recreationally active men. | CD31+/CD42b- | 1600 g for 15 min at 4°C | Morning following exercise bout | No change |
| |||||
Mobius-Winkler et al. [63] | 4 hr cycling at 70% IAT in young, healthy men. | CD42b−CD42b−/CD62E+ | 11,000g for 2 min | 16 predefined time points during and after finishing cycling. | No change |
| |||||
Jenkins et al. [74] | Exercise at 70% of VO2peak until 598 kcal was expended in recreationally, healthy active men. | CD31+/CD42b−CD62E+ | Double centrifugation of 1500g for 20 min at room temperature | (i) Pre-meal (ii) 1, 2, 3, and 4 hr postprandial |
↓CD31+/CD42b− ↓CD62E+ Unaffected by high-fat meal |
| |||||
Guiraud et al. [60] | Single session of HIIE: 15-second intervals at 100% of PPO and 15-second passive recovery intervals or isocaloric MICE in men with coronary heart disease. | CD31+ CD62E+ CD42b− CD42b+ |
1500g for 15 min followed by a single centrifugation at 13,000g for 2 min | (i) 10 min pre-ex (ii) 20 min post-ex (iii) 24 hr post-ex (iv) 72 hr post-ex |
No change |
| |||||
Ross et al. [62] | 3 sets of 6 resistance exercises at 15 RM w/o rest in young, trained men. | CD144+ CD146+ CD105+ |
1500g for 15 min followed by 13,000g for 2 min | (i) Pre-ex (ii) 10 min post-ex (iii) 2 hr post-ex (iv) 24 hr post-ex |
No change |
| |||||
Wahl et al. [67] | (1) HVT; 130 min at 55% PPO, (2) 4 × 4 min at 95% PPO, and (3) 4 × 30 sec all-out in healthy male, triathletes. | CD31+/CD42b− CD31/CD42b CD14/CD16 | 1.861g for 10 min at 4°C | (i) Pre-ex (ii) Immediately post-ex (iii) 60 min post-ex (iv) 180 min post-ex |
↓CD31+/CD42b− ↓CD31/CD42b ↓CD14/CD16 |
| |||||
Chanda et al. [61] | Acute strenuous exercise (treadmill running VO2peak) versus. moderate (75% HRmax for 45 min) in healthy females. | Total EVs CD41a |
2500 rpm for 5 min at 4°C | (i) Pre-ex (ii) Immediately post-ex (iii) 45 min post-ex |
↑Total EVs ↑CD41a Only after strenuous ex; No moderate ex change |
| |||||
Durrer et al. [72] | (1) HICE 20 min cycling at just above VT. (2) HIIE 10 × 1 min at 90% peak aerobic power in young, overweight, inactive males and females. |
CD62E+ CD31+/CD42b− |
Double centrifugation of 1500g for 15 min at room temperature | (i) Pre-ex (ii) Immediate post-ex (iii) Morning post-ex |
↑CD62E+ (females only) No change CD31+/CD42b− ↓CD62E+ (males only) ↓CD31+/CD42b− |
| |||||
Lansford et al. [69] | Acute bout at 60–75% VO2peak in healthy, active individuals |
CD62E+, CD34+ CD31+/CD42b− |
Double centrifugation of 1500g for 20 min at room temperature | (i) Pre-ex (ii) Post-ex |
↑CD62E+ in men ↑CD34+ in women No change CD31+/CD42b− |
| |||||
Wilhelm et al. [65] | 1 h of moderate- (46 ± 2% VO2peak) or heavy- (67 ± 2% VO2peak) intensity semirecumbent cycling in healthy, young men. | CD62E+ CD41+ |
17,500g for 1 hr at 4°C | (i) Pre-ex (ii) Post-ex |
↑CD41+ following heavy exercise No CD62E+ change |
| |||||
Bei et al. [114] | Exercise stress test in middle-aged, overweight men and women. | CD63+ | 1000g for 10 min and 2500g for 15 min at room temperature | (i) Rest (ii) Peak-ex (iii) Recovery (15 min after completion |
↑EV count |
| |||||
Whitham et al. [66] | 1 hr (30 min at 55%, 20 min at 70%, and ~10 min at 80% of VO2peak) in healthy males. | ACTN4, ADAM10, ALIX, ANAX11, and CD81 | 20,000g for 2x at 60 min | (i) Pre-ex (ii) Exercise (iii) 4 hr post-ex |
↑EV count |
IAT: individual anaerobic threshold; HIIE: high-intensity interval exercise; MICE: moderate-intensity continuous exercise; RM: repetition max; HVT: high-volume training; PPO: peak power output; HICE: high-intensity continuous exercise; VT: ventilatory threshold.