Figure 2.

Mitochondrial respiratory chain assessment and intracellular reactive oxygen species (ROS) generation by endothelial cells treated with normal glucose (NG) or high glucose (HG) plus P. albidus extract (PleExt). (a) Complex I activity. (b) Complex II activity. (c) Complex III activity. (d) ATP levels. (e) Intracellular ROS generation. Results are expressed as mean ± SD of at least three independent experiments. Different letters indicate significantly different values among the treatments according to the analysis of variance (ANOVA) and Tukey's post hoc test. Statistical significance was determined at p < 0.05.