Table 5.
Inflammatory response and clinical outcome.
| Inflammatory response 3–7 days after stroke | |||
|---|---|---|---|
| Variable | Outcome 7 days after stroke | P* | |
| NIHSS ≤15 | NIHSS >15 | ||
| WBC | 8.5 (6.0–12.7) | 11.6 (6.6–14.9) | 0.019 |
| Neutrophils | 5.7 (3.8–9.0) | 9.1 (4.6–11.0) | 0.002 |
| Lymphocytes | 1.67 (1.02–2.34) | 1.19 (0.90–2.08) | 0.052 |
| Monocytes | 0.82 (0.52–1.25) | 0.88 (0.53–1.26) | 0.622 |
| Eosinophils | 0.20 (0.04–0.42) | 0.13 (0.02–0.31) | 0.136 |
| Basophils | 0.04 (0.02–0.08) | 0.03 (0.02–0.07) | 0.226 |
| T-cells | 1.16 (0.66–1.61) | 0.86 (0.59–1.25) | 0.005 |
| Helper T-cells | 0.77 (0.45–1.14) | 0.55 (0.38–0.92) | 0.013 |
| Cytotoxic T-cells | 0.37 (0.18–0.68) | 0.28 (0.16–0.39) | 0.041 |
| Natural killer cells | 0.24 (0.12–0.41) | 0.20 (0.08–0.46) | 0.264 |
| DR+ T-cells | 0.075 (0.032–0.170) | 0.054 (0.037–0.145) | 0.218 |
| B-cells | 0.19 (0.08–0.38) | 0.19 (0.08–0.44) | 0.595 |
| CD14+ cells | 0.68 (0.39–1.13) | 0.83 (0.45–1.17) | 0.308 |
| DR+ monocytes | 0.63 (0.37–0.97) | 0.62 (0.41–0.94) | 0.976 |
| CD16+ monocytes | 0.087 (0.041–0.159) | 0.107 (0.044–0.161) | 0.286 |
| Calprotectin | 6.0 (2.9–10.7) | 5.7 (3.9–12.7) | 0.383 |
| Inflammatory response 3–7 days after stroke | |||
| Variable | Outcome after 3 months | P* | |
| mRS 0–2 (n=49) | mRS 3–6 (n=56) | ||
| WBC | 8.1 (5.8–11.4) | 9.6 (6.6–13.7) | 0.061 |
| Neutrophils | 5.3 (3.1–7.9) | 6.8 (4.1–10.7) | 0.002 |
| Lymphocytes | 1.73 (1.29–2.78) | 1.47 (0.88–2.28) | 0.013 |
| Monocytes | 0.81 (0.48–1.18) | 0.88 (0.57–1.25) | 0.345 |
| Eosinophils | 0.20 (0.03–0.42) | 0.18 (0.04–0.35) | 0.231 |
| Basophils | 0.04 (0.02–0.08) | 0.04 (0.02–0.08) | 0.487 |
| T-cells | 1.27 (0.90–1.94) | 1.08 (0.64–1.56) | 0.006 |
| Helper T-cells | 0.81 (0.59–1.23) | 0.73 (0.36–1.06) | 0.006 |
| Cytotoxic T-cells | 0.38 (0.19–0.82) | 0.33 (0.16–0.62) | 0.090 |
| Natural killer cells | 0.25 (0.13–0.41) | 0.20 (0.10–0.38) | 0.127 |
| DR+ T-cells | 0.09 (0.04–0.19) | 0.07 (0.03–0.17) | 0.127 |
| B-cells | 0.19 (0.11–0.47) | 0.18 (0.06–0.38) | 0.243 |
| CD14+ cells | 0.66 (0.37–0.96) | 0.77 (0.48–1.17) | 0.114 |
| DR+ monocytes | 0.62 (0.35–0.92) | 0.65 (0.43–0.97) | 0.259 |
| CD16+ monocytes | 0.086 (0.036–0.198) | 0.103 (0.043–0.160) | 0.311 |
| Calprotectin | 5.8 (2.5–10.9) | 6.0 (4.3–12.6) | 0.066 |
*
P-values of the Mann-Whitney U test were computed to compare patients with different outcomes.
National Institutes of Health Stroke Scale (NIHSS).