Table 6.
Inflammatory responses.
| Inflammatory response | |||
|---|---|---|---|
| Variable | Time of measurement | P* | |
| Entry | After 3–7 days | ||
| WBC | 9.1 (6.1–13.0) | 8.8 (6.2–12.9) | 0.113 |
| Neutrophils | 6.8 (4.4–11.0) | 5.8 (3.9–9.9) | <0.001 |
| Lymphocytes | 1.23 (0.72–2.16) | 1.67 (1.01–2.57) | <0.001 |
| Monocytes | 0.58 (0.35–0.96) | 0.83 (0.52–1.27) | <0.001 |
| Eosinophils | 0.1 (0.0–0.2) | 0.2 (0.0–0.4) | <0.001 |
| Basophils | 0.04 (0.02–0.07) | 0.04 (0.02–0.08) | 0.654 |
| T-cells | 0.82 (0.43–1.50) | 1.15 (0.66–1.70) | <0.001 |
| Helper T-cells | 0.50 (0.27–1.01) | 0.75 (0.42–1.15) | <0.001 |
| Cytotoxic T-cells | 0.26 (0.11–0.54) | 0.35 (0.18–0.70) | 0.003 |
| Natural killer cells | 0.19 (0.09–0.46) | 0.23 (0.12–0.42) | 0.218 |
| DR+ T-cells | 0.061 (0.027–0.138) | 0.072 (0.033–0.173) | 0.052 |
| B-cells | 0.14 (0.06–0.29) | 0.19 (0.08–0.42) | <0.001 |
| CD14+ cells | 0.48 (0.28–0.80) | 0.71 (0.41–1.17) | <0.001 |
| DR+ monocytes | 0.45 (0.27–0.76) | 0.62 (0.38–0.95) | <0.001 |
| CD16+ monocytes | 0.039 (0.016–0.091) | 0.093 (0.039–0.162) | <0.001 |
| Calprotectin | 4.9 (2.6–9.8) | 5.8 (2.9–11.1) | 0.043 |
| Inflammatory response 3–7 days after stroke | |||
| Variable | Treatment in Cerebral Ischemia (TICI) score | P** | |
| 0-1 | 2-3 | ||
| WBC | 11.2 (7.3–13.7) | 8.5 (6.0–12.8) | 0.019 |
| Neutrophils | 8.3 (5.1–11.0) | 5.6 (3.8–9.3) | 0.006 |
| Lymphocytes | 1.2 (1.0–2.9) | 1.7 (1.0–2.5) | 0.307 |
| Monocytes | 0.90 (0.65–1.27) | 0.82 (0.50–1.26) | 0.426 |
| Eosinophils | 0.11 (0.03–0.27) | 0.19 (0.04–0.42) | 0.289 |
| Basophils | 0.04 (0.02–0.07) | 0.04 (0.02–0.08) | 0.454 |
| T-cells | 0.92 (0.60–1.96) | 1.15 (0.70–1.68) | 0.244 |
| Helper T-cells | 0.67 (0.39–1.14) | 0.75 (0.43–1.15) | 0.478 |
| Cytotoxic T-cells | 0.23 (0.18–0.83) | 0.37 (0.18–0.68) | 0.095 |
| Natural killer cells | 0.25 (0.06–0.42) | 0.22 (0.12–0.42) | 0.908 |
| DR+ T-cells | 0.049 (0.040–0.266) | 0.074 (0.032–0.172) | 0.490 |
| B-cells | 0.20 (0.13–0.38) | 0.19 (0.08–0.42) | 0.631 |
| CD14+ cells | 0.80 (0.55–1.18) | 0.69 (0.40–1.16) | 0.289 |
| DR+ monocytes | 0.60 (0.46–0.93) | 0.63 (0.37–0.95) | 0.694 |
| CD16+ monocytes | 0.114 (0.055–0.180) | 0.087 (0.039–0.162) | 0.242 |
| Calprotectin | 6.4 (3.4–11.3) | 5.8 (2.7–11.0) | 0.387 |
*
P-values of the paired sign test were computed to compare the inflammatory response at different time points;
**
P-values of the Mann-Whitney U test were computed to compare patients with different outcome.