Figure 1.

qPCR and SNP array analysis at the TRG locus. (A) ABD status by qPCR TRG:ANLN fold change of WGA diagnostic samples from 149 patients. Three patients with an indeterminate result are not shown as their blast counts were <50%. (B) Representative Log-R ratio plot at the TRG locus (GRCh37/hg19 chr7:37868112-38678273) from CytoSNP-850K arrays for an ABD and (C) a non-ABD patient. Location of the V-J region amplified in the qPCR assay is shown. ABD: Absence of Biallelic Deletion; qPCR: quantitative polymerase chain reaction; IND: indeterminate.