Table 1.
Data are count or mean (±SD). Disease duration is defined as time since diagnosis. Abbreviations: F = females; L = left; LEDD = levodopa equivalent daily dose; M = males; MoCA = Montreal Cognitive Assessment; MDS-UPDRS-III = the motor section of the Movement Disorder Society Unified Parkinson's Disease Rating Scale; mg = milligram; MVC = maximum voluntary contraction; N = Newtons; R = right; yrs. = years.
| Demographics|clinical data | Parkinson's disease |
Healthy control | Paired T-test |
Group T-test |
|
|---|---|---|---|---|---|
| OFF-medication | ON-medication | p-Value | p-Value | ||
| Sample size | 15 | 15 | |||
| Age, yrs | 62.00 (10.51) | 62.53 ± 8.44 | 0.931 | ||
| Gender (M|F) | 9 | 6 | 9|6 | |||
| Handedness (L|R) | 3 | 12 | 3|12 | |||
| MDS-UPDRS-III – Total | 16.80 (8.51) | 13.13 (6.98) | 1.6 (±1.72) | <0.001 | <0.001 |
| MoCA | 27.20 (2.18) | 27.67 (1.54) | 27.80 (±2.01) | 0.301 | 0.574 |
| Total LEDD, mg | 649.00 (378.93) | ||||
| MVC, N | 66.93 (22.71) | ||||
| Disease duration, yrs | 5.17 (4.78) | ||||
| Hoehn and Yahr stage (OFF) | 1.67 (0.62) | ||||
| More affected side (L|R) | 7|8 | ||||