Strawberries and aspirin suppressed esophageal tumor cell proliferation. Rat esophagi were collected and analyzed with western blotting to examine the expression of PCNA, cyclin D1,cyclin A2, and CDK4. All three study diets significantly suppressed cell proliferation but had no significant effects on cell cycle regulation. n = 4–6, *p < 0.05, **p < 0.01, ***p < 0.001.