Fig 4. Effect of AKBA treatment on proliferation and intra-tumoral microvessel density in an ectopic GBM model.

Formalin-fixed paraffin-embedded sections were stained immunohistochemically for Ki-67 (proliferation marker) and CD31 (endothelial marker). Representative microphotographs from each treatment group are shown (original magnification x400 –Ki-67, x200- CD31).