Table 2. CalcuSin analysis of AKBA and radiation combined treatment of GBM cells.
AKBA (μM) | Radiation (Gy) | Combination Index (CI) | |||
---|---|---|---|---|---|
U87 | U251 | LN319 | A172 | ||
10 | 2 | 1.546 | 1.495 | 0.793 | 0.726 |
10 | 4 | 1.281 | 1.206 | 2.246 | 1.232 |
10 | 6 | 1.13 | 1.236 | 1.119 | 1.007 |
20 | 2 | 1.237 | 1.571 | 1.093 | 1.001 |
20 | 4 | 1.22 | 1.101 | 1.215 | 1.19 |
20 | 6 | 1.098 | 1.163 | 0.773 | 1.175 |
30 | 2 | 1.855 | 2.248 | 1.435 | 1.012 |
30 | 4 | 1.404 | 1.368 | 1.166 | 1.104 |
30 | 6 | 1.172 | 1.528 | 1.046 | 1.05 |
40 | 2 | 1.255 | 1.017 | 0.900 | 0.464 |
40 | 4 | 0.888 | 0.981 | 0.824 | 0.741 |
40 | 6 | 0.914 | 1.253 | 0.852 | 0.813 |