Table 2.
Case no. | Age, years | Sex | Classification | WHO grade | Side | Location | IDHmut | 1p | 19q | 10q | p53mut | TERTmut | Oligodendroglial component | Neuropil‐like island | Adjuvant |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 29 | M | AA, IDHmut | III | L | Fr | R132H | Intact | Loss | Intact | F113del | Wt | + | − | RT + TMZ |
2 | 33 | M | AA, IDHmut | III | R | Fr | R132H | Intact | Loss | Intact | G266R | Wt | + | − | RT + TMZ |
3 | 40 | M | AA, IDHmut | III | L | Fr | R132H | Intact | Loss | Intact | H179N | Wt | + | + | RT + TMZ |
4 | 40 | M | AA, IDHmut | III | R | Fr | R132H | Intact | Partial loss | Intact | R273C | Wt | + | + | RT + TMZ |
5 | 50 | M | AA, IDHmut | III | R | Fr | R132H | Intact | Loss | Intact | D49H | Wt | + | + | RT + TMZ |
6 | 56 | F | AA, IDHmut | III | R | Fr | R132H | Intact | Loss | Loss | C141Y | Wt | + | − | RT + TMZ |
7 | 57 | M | AA, IDHmut | III | L | Fr | R132H | Intact | Loss | Intact | P80 fs | Wt | + | + | PAV |
8 | 40 | M | GBM, IDHwt | IV | L | Fr | Wt | Intact | Loss | Intact | Nd | Nd | + | − | RT + TMZ |
9 | 51 | M | GBM, IDHwt | IV | L | Fr | Wt | Intact | Loss | Loss | Nd | Nd | + | − | RT + TMZ |
10 | 52 | M | GBM, IDHwt | IV | R | Fr | Wt | Intact | Loss | Loss | Nd | Nd | − | − | RT + TMZ |
11 | 55 | F | GBM, IDHwt | IV | R | P | Wt | Intact | Loss | Loss | Nd | Nd | − | − | RT + TMZ |
12 | 58 | F | GBM, IDHwt | IV | L | P | Wt | Intact | Loss | Loss | Nd | Nd | + | − | RT + TMZ |
13 | 59 | F | GBM, IDHwt | IV | R | T | Wt | Intact | Loss | Loss | Nd | Nd | − | − | RT + TMZ |
14 | 60 | M | GBM, IDHwt | IV | R | T | Wt | Intact | Loss | Intact | Nd | Nd | + | − | RT + TMZ |
15 | 66 | M | GBM, IDHwt | IV | R | Fr | Wt | Intact | Loss | Loss | Nd | Nd | + | − | RT + PAV |
16 | 66 | M | GBM, IDHwt | IV | R | Fr | Wt | Intact | Loss | Loss | Nd | Nd | + | − | RT + PAV |
17 | 71 | M | GBM, IDHwt | IV | L | P | Wt | Intact | Loss | Intact | Nd | Nd | − | − | RT + TMZ |
18 | 76 | M | GBM, IDHwt | IV | L | P | Wt | Intact | Loss | Partial loss | Nd | Nd | − | − | RT + TMZ |
19 | 77 | M | GBM, IDHwt | IV | R | Fr | Wt | Intact | Loss | Intact | Nd | Nd | + | − | RT + TMZ |
20 | 78 | M | GBM, IDHwt | IV | R | T | Wt | Intact | Loss | Loss | Nd | Nd | + | − | RT + TMZ |
21 | 83 | F | GBM, IDHwt | IV | L | P | Wt | Intact | Loss | Loss | Nd | Nd | − | − | RT + TMZ |
AA, anaplastic astrocytoma; F, female; Fr, frontal lobe; GBM, glioblastoma; L, left; M, male; mut, mutant; Nd, no data; P, parietal lobe; PAV, procarbazine, ACNU, vincristine; R, right; RT, radiation therapy; T, temporal lobe; TMZ, temozolomide; Wt, wild type;