Figure 5.

Silencing ONECUT‐2 (OC‐2) inhibits the expression of angiogenesis‐related factors. A, Vascular endothelial growth factor A (VEGFA) expression in COV‐504 and SKOV3 cells after transfection with OC2‐siRNAs for 48 h. B, OC‐2 expression was detected after overexpression of VEGFA. C, VEGFA expression in COV‐504 and SKOV3 cells was detected after transfection with siRNA‐VEGFA for 48 h. D, Hepatocyte growth factor (HGF) and hypoxia‐inducible factor‐1α (HIF‐1α) mRNA expression were detected by real‐time PCR. E, mRNA expression of VEGFC and fibroblast growth factor 2 (FGF2) were detected by real‐time PCR. Data were represented as the means ± SD. *P < .05, **P < .01. ACTB, β‐actin; NC, scrambled siRNA